International Journal of Biological Sciences

Volume 3 (7); 2007

Editorial

In Celebration of Dr. Mario R. Capecchi's Nobel Prize
Chuxia Deng
Int. J. Biol. Sci. 2007, 3: 417-419
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Short Research Communication

Concerted Transcriptional Regulation by BRCA1 and COBRA1 in Breast Cancer Cells
Sarah E. Aiyar, HyungJun Cho, Jae Lee, Rong Li
Int. J. Biol. Sci. 2007, 3: 486-492
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

DNA damage repair is unaffected by mimicked heterozygous levels of BRCA2 in HT-29 cells
Brian Tannenbaum, Tobechukwu Mofunanya, Alan R. Schoenfeld
Int. J. Biol. Sci. 2007, 3: 402-407
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Charles River Sprague Dawley Rats Lack Early Age-Dependent Susceptibility to DMBA-Induced Mammary Carcinogenesis
R.B. Gear, M. Yan, J. Schneider, P. Succop, S.C. Heffelfinger, D.J. Clegg
Int. J. Biol. Sci. 2007, 3: 408-416
[Abstract] [Full text] [PDF] [PubMed] [PMC]

cDNA Cloning and Overexpression of Acidic Ribosomal Phosphoprotein P1 Gene (RPLP1) from the Giant Panda
Yu-Jie Du, Xiao-Yan Luo, Yan-Zhe Hao, Tian Zhang, Wan-Ru Hou
Int. J. Biol. Sci. 2007, 3: 428-433
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Phycobilisomes linker family in cyanobacterial genomes: divergence and evolution
Xiangyu Guan, Song Qin, Fangqing Zhao, Xiaowen Zhang, Xuexi Tang
Int. J. Biol. Sci. 2007, 3: 434-445
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Immunoregulatory role of intestinal surfactant-like particles during Salmonella typhimurium infection
M. Hanief Sofi, Archana Bhatnagar, Saveeta Sapra, Akhtar Mahmood, Sidhartha Majumdar
Int. J. Biol. Sci. 2007, 3: 446-454
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Adjuvant effect of anti-4-1BB mAb administration in adoptive T cell therapy of cancer
Qiao Li, Takekazu Iuchi, Maria N. Jure-Kunkel, Alfred E. Chang
Int. J. Biol. Sci. 2007, 3: 455-462
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Rational Design of Analyte Channels of the Green Fluorescent Protein for Biosensor Applications
Natta Tansila, Tanawut Tantimongcolwat, Chartchalerm Isarankura-Na-Ayudhya, Chanin Nantasenamat, Virapong Prachayasittikul
Int. J. Biol. Sci. 2007, 3: 463-470
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Growth-hormone inducible transmembrane protein (Ghitm) belongs to the Bax inhibitory protein-like family
Kerstin Reimers, Claudia YU Choi, Vesna Bucan, Peter M Vogt
Int. J. Biol. Sci. 2007, 3: 471-476
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Smad3 -signalling and Th2 cytokines in normal mouse airways and in a mouse model of asthma
Minna Anthoni, Guoying Wang, Marina S. Leino, Antti I. Lauerma, Harri T. Alenius, Henrik J. Wolff
Int. J. Biol. Sci. 2007, 3: 477-485
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Candidate Gene Identification Approach: Progress and Challenges
Mengjin Zhu, Shuhong Zhao
Int. J. Biol. Sci. 2007, 3: 420-427
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (6); 2007

Short Research Communication

High level glucose increases mutagenesis in human lymphoblastoid cells
Ying Zhang, Junqing Zhou, Tieli Wang, Lu Cai
Int. J. Biol. Sci. 2007, 3: 375-379
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Versican Expression during Synovial Joint Morphogenesis
John B. Shepard, Heidi A. Krug, Brooklynn A. LaFoon, Stanley Hoffman, Anthony A. Capehart
Int. J. Biol. Sci. 2007, 3: 380-384
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

Differences in Apoptosis and Cell Cycle Distribution between Human Melanoma Cell Lines UACC903 and UACC903(+6), before and after UV Irradiation
Qiuyang Zhang, Yuanbin Chen, Bi-Dar Wang, Ping He, Yan A. Su
Int. J. Biol. Sci. 2007, 3: 342-348
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Superoxide Anion Radical Scavenging Activities of Herbs and Pastures in Northern Japan Determined Using Electron Spin Resonance Spectrometry
Mohammad Al-Mamun, Koji Yamaki, Toshiki Masumizu, Yumi Nakai, Katsumi Saito, Hiroaki Sano, Yoshifumi Tamura
Int. J. Biol. Sci. 2007, 3: 349-355
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The Amphioxus SoxB Family: Implications for the Evolution of Vertebrate Placodes
Daniel Meulemans, Marianne Bronner-Fraser
Int. J. Biol. Sci. 2007, 3: 356-364
[Abstract] [Full text] [PDF] [PubMed] [PMC]

An mRNA-protein Fusion at N-terminus for Evolutionary Protein Engineering
Shingo Ueno, Hidenao Arai, Miho Suzuki, Yuzuru Husimi
Int. J. Biol. Sci. 2007, 3: 365-374
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reversal of Systemic Hypertension-Associated Cardiac Remodeling in Chronic Pressure Overload Myocardium by Ciglitazone
Brooke C. Henderson, Utpal Sen, Corey Reynolds, Karni S. Moshal, Alexander Ovechkin, Neetu Tyagi, Ganesh K. Kartha, Walter E. Rodriguez, Suresh C. Tyagi
Int. J. Biol. Sci. 2007, 3: 385-392
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Thermal injury-plus-sepsis contributes to a substantial deletion of intestinal mesenteric lymph node CD4⁺ T cell via apoptosis
Nadeem Fazal, Walid M Al-Ghoul
Int. J. Biol. Sci. 2007, 3: 393-401
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (5); 2007

Research Paper

Proteomics Analysis of the Expression of Neurogranin in Murine Neuroblastoma (Neuro-2a) Cells Reveals Its Involvement for Cell Differentiation
Nian-Lin Reena Han, Jing Wen, Qingsong Lin, Pei Ling Tan, Yih-Cherng Liou, Fwu-Shan Sheu
Int. J. Biol. Sci. 2007, 3: 263-273
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Development of a highly sensitive and selective microplate chemiluminescence enzyme immunoassay for the determination of free thyroxine in human serum
Xu Wang, Hui Chen, Jin-Ming Lin, Xitang Ying
Int. J. Biol. Sci. 2007, 3: 274-280
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Effects of BRCA1 Transgene Expression on Murine Mammary Gland Development and Mutagen-Induced Mammary Neoplasia
Arichika Hoshino, Cindy J. Yee, Mel Campbell, Randall L. Woltjer, Rebecca L. Townsend, Riet van der Meer, Yu Shyr, Jeffrey T. Holt, Harold L. Moses, Roy A. Jensen
Int. J. Biol. Sci. 2007, 3: 281-291
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Human Maf1 negatively regulates RNA Polymerase III transcription via the TFIIB family members Brf1 and Brf2
Janet Rollins, Ingrid Veras, Stephanie Cabarcas, Ian Willis, Laura Schramm
Int. J. Biol. Sci. 2007, 3: 292-302
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Reduced Risk of Human Lung Cancer by Selective Cyclooxygenase 2 (Cox-2) Blockade: Results of a Case Control Study
Randall E. Harris, Joanne Beebe-Donk, Galal A. Alshafie
Int. J. Biol. Sci. 2007, 3: 328-334
[Abstract] [Full text] [PDF] [PubMed] [PMC]

The responses of HT22 cells to the blockade of mitochondrial complexes and potential protective effect of selenium supplementation
Jun Panee, Wanyu Liu, Kyoko Nakamura, Marla J. Berry
Int. J. Biol. Sci. 2007, 3: 335-341
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

The Forces Behind Cell Movement
Revathi Ananthakrishnan, Allen Ehrlicher
Int. J. Biol. Sci. 2007, 3: 303-317
[Abstract] [Full text] [PDF] [PubMed] [PMC]

In search of a function for the most frequent naturally-occurring length polymorphism (MFNLP) of the HIV-1 LTR: Retaining functional coupling, of Nef and RBF-2, at RBEIII?
Mario Clemente Estable
Int. J. Biol. Sci. 2007, 3: 318-327
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (4); 2007

Research Paper

Overexpression of Selenoprotein H Reduces Ht22 Neuronal Cell Death after UVB Irradiation by Preventing Superoxide Formation
Kamel E. Ben Jilani, Jun Panee, Qingping He, Marla J. Berry, Ping-An Li
Int. J. Biol. Sci. 2007, 3: 198-204
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Structural stability and endonuclease activity of a PI-SceI GFP-fusion protein
Alireza G. Senejani, J. Peter Gogarten
Int. J. Biol. Sci. 2007, 3: 205-211
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Characterization of transcriptional regulation of neurogranin by nitric oxide and the role of neurogranin in SNP-induced cell death: implication of neurogranin in an increased neuronal susceptibility to oxidative stress
Jingang Gui, Yan Song, Nian-Lin Reena Han, Fwu-Shan Sheu
Int. J. Biol. Sci. 2007, 3: 212-224
[Abstract] [Full text] [PDF] [PubMed] [PMC]

MCEF is localized to the nucleus by protein sequences encoded within three distinct exons, where it represses HIV-1 Tat-transactivation of LTR-directed transcription
Maksymilian F. Niedzielski, Robert Hopewell, Zohra Ismail, Mario C. Estable
Int. J. Biol. Sci. 2007, 3: 225-236
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Tyrosine Sulfation of Statherin
C. Kasinathan, N. Gandhi, P. Ramaprasad, P. Sundaram, N. Ramasubbu
Int. J. Biol. Sci. 2007, 3: 237-241
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Silencing of the Pink1 Gene Expression by Conditional RNAi Does Not Induce Dopaminergic Neuron Death in Mice
Hongxia Zhou, Björn H Falkenburger, Jörg B Schulz, Kim Tieu, Zuoshang Xu, Xu Gang Xia
Int. J. Biol. Sci. 2007, 3: 242-250
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A polychromator-based microspectrophotometer
Valter Evangelista, Mauro Evangelisti, Laura Barsanti, Anna Maria Frassanito, Vincenzo Passarelli, Paolo Gualtieri
Int. J. Biol. Sci. 2007, 3: 251-256
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Enrichment of coenzyme Q10 in plasma and blood cells: defense against oxidative damage
Petra Niklowitz, Anka Sonnenschein, Bernd Janetzky, Werner Andler, Thomas Menke
Int. J. Biol. Sci. 2007, 3: 257-262
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (3); 2007

Editorial

Swine Genome Science Comes of Age
Zhihua Jiang, Max F. Rothschild
Int. J. Biol. Sci. 2007, 3: 129-131
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Advances in Swine Transcriptomics
Christopher K. Tuggle, Yanfang Wang, Oliver Couture
Int. J. Biol. Sci. 2007, 3: 132-152
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Genetic Resources, Genome Mapping and Evolutionary Genomics of the Pig (Sus scrofa)
Kefei Chen, Tara Baxter, William M. Muir, Martien A. Groenen, Lawrence B. Schook
Int. J. Biol. Sci. 2007, 3: 153-165
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Characterizing Linkage Disequilibrium in Pig Populations
Feng-Xing Du, Archie C. Clutter, Michael M. Lohuis
Int. J. Biol. Sci. 2007, 3: 166-178
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Advances in Swine Biomedical Model Genomics
Joan K. Lunney
Int. J. Biol. Sci. 2007, 3: 179-184
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Identifying the Future Needs for Long-Term USDA Efforts in Agricultural Animal Genomics
R. D. Green, M. A. Qureshi, J. A. Long, P.J. Burfening, D.L. Hamernik
Int. J. Biol. Sci. 2007, 3: 185-191
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Advances in QTL Mapping in Pigs
Max F. Rothschild, Zhi-liang Hu, Zhihua Jiang
Int. J. Biol. Sci. 2007, 3: 192-197
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (2); 2007

Short Research Communication

Role of TAB1 in nitric oxide-induced p38 activation in insulin-producing cells
Natalia Makeeva, Godfried M. Roomans, Nils Welsh
Int. J. Biol. Sci. 2007, 3: 71-76
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

The Environmental-Endocrine Basis of Gynandromorphism (Intersex) in a Crustacean
Allen W. Olmstead, Gerald A. LeBlanc
Int. J. Biol. Sci. 2007, 3: 77-84
[Abstract] [Full text] [PDF] [PubMed] [PMC]

A complete mitochondrial genome sequence of Asian black bear Sichuan subspecies (Ursus thibetanus mupinensis)
Wan-ru Hou, Yu Chen, Xia Wu, Jin-chu Hu, Zheng-song Peng, Jung Yang, Zong-xiang Tang, Cai-Quan Zhou, Yu-ming Li, Shi-kui Yang, Yu-jie Du, Ling-lu Kong, Zheng-long Ren, Huai-yu Zhang, Su-rong Shuai
Int. J. Biol. Sci. 2007, 3: 85-90
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Mouse 24p3 Protein Has an Effect on L929 Cell Viability
Pei-Tzu Li, Ying-Chu Lee, Namasivayam Elangovan, Sin-Tak Chu
Int. J. Biol. Sci. 2007, 3: 100-107
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Essential role of Elovl4 in very long chain fatty acid synthesis, skin permeability barrier function, and neonatal survival
D. Joshua Cameron, Zongzhong Tong, Zhenglin Yang, Jack Kaminoh, Shin Kamiyah, Haoyu Chen, Jiexi Zeng, Yali Chen, Ling Luo, Kang Zhang
Int. J. Biol. Sci. 2007, 3: 111-119
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Depletion of ceramides with very long chain fatty acids causes defective skin permeability barrier function, and neonatal lethality in ELOVL4 deficient mice
Wenmei Li, Roger Sandhoff, Mari Kono, Patricia Zerfas, Vickie Hoffmann, Bryan Char-Hoa Ding, Richard L. Proia, Chu-Xia Deng
Int. J. Biol. Sci. 2007, 3: 120-128
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Technical Report

RNAi-based conditional gene knockdown in mice using a U6 promoter driven vector
Vivek Shukla, Xavier Coumoul, Chu-Xia Deng
Int. J. Biol. Sci. 2007, 3: 91-99
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Letter To The Editor

Application of Nanotechnology in Cancer Research: Review of Progress in the National Cancer Institute's Alliance for Nanotechnology
Beeta Ehdaie
Int. J. Biol. Sci. 2007, 3: 108-110
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Volume 3 (1); 2007

Short Research Communication

Gamma Protocadherin Expression in the Embryonic Chick Nervous System
Kenneth D. Cronin, Anthony A. Capehart
Int. J. Biol. Sci. 2007, 3: 8-11
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Intrarenal Oxidative Stress and Augmented Angiotensinogen are Precedent to Renal Injury in Zucker Diabetic Fatty Rats
Yuki Suzaki, Yuri Ozawa, Hiroyuki Kobori
Int. J. Biol. Sci. 2007, 3: 40-46
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Prion-derived copper-binding peptide fragments catalyze the generation of superoxide anion in the presence of aromatic monoamines
Tomonori Kawano
Int. J. Biol. Sci. 2007, 3: 57-63
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Research Paper

Effect of Reparation of Repeat Sequences in the Human α-Synuclein on Fibrillation Ability
Koji Sode, Sayaka Ochiai, Natsuki Kobayashi, Eri Usuzaka
Int. J. Biol. Sci. 2007, 3: 1-7
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Increased Susceptibility to Metabolic Alterations in Young Adult Females Exposed to Early Malnutrition
María del Carmen Miñana-Solis, Carolina Escobar
Int. J. Biol. Sci. 2007, 3: 12-19
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Proteomic Identification of 14-3-3ζ as an Adapter for IGF-1 and Akt/GSK-3β Signaling and Survival of Renal Mesangial Cells
Lalit P. Singh, Yan Jiang, Davis W. Cheng
Int. J. Biol. Sci. 2007, 3: 27-39
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Distinct domain-dependent effect of syntaxin1A on amiloride-sensitive sodium channel (ENaC) currents in HT-29 colonic epithelial cells
Sunil K Saxena, Madhurima Singh, Simarna Kaur, Constantine George
Int. J. Biol. Sci. 2007, 3: 47-56
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Urokinase Separation from Cell Culture Broth of a Human Kidney Cell Line
Vibha Bansal, Pradip K. Roychoudhury, Ashok Kumar
Int. J. Biol. Sci. 2007, 3: 64-70
[Abstract] [Full text] [PDF] [PubMed] [PMC]

Review

Are heat shock proteins therapeutic target for Parkinson's disease?
Guang-Rui Luo, Sheng Chen, Wei-Dong Le
Int. J. Biol. Sci. 2007, 3: 20-26
[Abstract] [Full text] [PDF] [PubMed] [PMC]